Deep brain stimulation for tremor in multiple sclerosis - Consensus recommendations of the German Deep Brain Stimulation Association

Timmermann, L. and Deuschl, G. and Fogel, W. and Hilker, R. and Kupsch, A. and Lange, M. and Schrader, C. and Sixel-Doering, F. and Volkmann, J. and Benecke, R. (2009) Deep brain stimulation for tremor in multiple sclerosis - Consensus recommendations of the German Deep Brain Stimulation Association. NERVENARZT, 80 (6). 673-+. ISSN 0028-2804,

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Abstract

Deep brain stimulation (DBS) in the nucleus ventralis intermedius thalami (VIM) is a common procedure to treat disabling tremor in multiple sclerosis which is refractory to pharmacological treatment. The sparse studies on DBS in multiple sclerosis tremor remain controversial regarding the clinical effect on postural and action tremor of hands, trunk and head. Furthermore, it remains unclear whether DBS in multiple sclerosis tremor is superior to thalamotomy and whether patients show an overall improvement in quality of life and activities of daily living. Therefore, the consensus recommendations of the German Deep Brain Stimulation Study Group rely primarily on expert opinion and include (1) extensive preoperative characterisation of tremor, ataxia with accompanying disabilities, status of the multiple sclerosis, co-morbidities and burden of disease, (2) careful intraoperative testing of effects and side effects and (3) intensive postoperative testing and programming as well as regular re-evaluation of the therapeutic effect.

Item Type: Article
Uncontrolled Keywords: CHRONIC THALAMIC-STIMULATION; MOVEMENT-DISORDERS; THALAMOTOMY; MANAGEMENT; Deep brain stimulation; Tremor; Multiple sclerosis; Neurological consensus recommendations
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Neurochirurgie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 14 Sep 2020 08:36
Last Modified: 14 Sep 2020 08:36
URI: https://pred.uni-regensburg.de/id/eprint/28909

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