Grimm, Daniela and Grosse, Jirka and Wehland, Markus and Mann, Vivek and Reseland, Janne Elin and Sundaresan, Alamelu and Corydon, Thomas Juhl (2016) The impact of microgravity on bone in humans. BONE, 87. pp. 44-56. ISSN 8756-3282, 1873-2763
Full text not available from this repository. (Request a copy)Abstract
Experiencing real weightlessness in space is a dream for many of us who are interested in space research. Although space traveling fascinates us, it can cause both short-term and long-term health problems. Microgravity is the most important influence on the human organism in space. The human body undergoes dramatic changes during a long-term spaceflight. In this review, we will mainly focus on changes in calcium, sodium and bone metabolism of space travelers. Moreover, we report on the current knowledge on the mechanisms of bone loss in space, available models to simulate the effects of microgravity on bone on Earth as well as the combined effects of microgravity and cosmic radiation on bone. The available countermeasures applied in space will also be evaluated. (C) 2016 Elsevier Inc. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | LONG-DURATION SPACEFLIGHT; THYROID-CANCER CELLS; RENAL STONE RISK; BODY NEGATIVE-PRESSURE; DIFFERENTIAL GENE-EXPRESSION; RESISTIVE VIBRATION EXERCISE; PARABOLIC FLIGHT MANEUVERS; TAIL-SUSPENDED RATS; PROLONGED BED REST; HUMAN SPACE-FLIGHT; Microgravity; Metabolism; Calcium; Bone loss; Countermeasures |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Abteilung für Nuklearmedizin |
| Depositing User: | Petra Gürster |
| Date Deposited: | 02 Sep 2020 06:35 |
| Last Modified: | 02 Sep 2020 06:35 |
| URI: | https://pred.uni-regensburg.de/id/eprint/2893 |
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