Vorwerk, Hilke and Beckmann, Gabriele and Bremer, Michael and Degen, Maria and Dietl, Barbara and Fietkau, Rainer and Gsaenger, Tammo and Hermann, Robert Michael and Herrmann, Markus Karl Alfred and Hoeller, Ulrike and van Kampen, Michael and Koerber, Wolfgang and Maier, Burkhard and Martin, Thomas and Metz, Michael and Richter, Ronald and Siekmeyer, Birgit and Steder, Martin and Wagner, Daniela and Hess, Clemens Friedrich and Weiss, Elisabeth and Christiansen, Hans (2009) The delineation of target volumes for radiotherapy of lung cancer patients. RADIOTHERAPY AND ONCOLOGY, 91 (3). pp. 455-460. ISSN 0167-8140,
Full text not available from this repository. (Request a copy)Abstract
Purpose: Differences in the delineation of the gross target volume (GTV) and planning target volume (PTV) in patients with non-small-cell lung cancer are considerable. The focus of this work is on the analysis of observer-related reasons while controlling for other variables. Methods: In three consecutive patients, eighteen physicians from fourteen different departments delineated the GTV and M in CT-slices using a detailed instruction for target delineation. Differences in the volumes, the delineated anatomic lymph node compartments and differences in every delineated pixel of the contoured volumes in the CT-slices (pixel-by-pixel-analysis) were evaluated for different groups: ten radiation oncologists from ten departments (ROs), four haematologic oncologists and chest physicians from four departments (HOs) and five radiation oncologists from one department (RO1D). Results: Agreement (overlap >= 70% of the contoured pixels) for the GTV and PTV delineation was found in 16.3% and 23.7% (ROs), 30.4% and 38.6% (HOs) and 32.8% and 35.9% (RO1D), respectively. Conclusion: A large interobserver variability in the PTV and much more in the GTV delineation were observed in spite of a detailed instruction for delineation. The variability was smallest for group RO1D where due to repeated discussions and uniform teaching a better agreement was achieved. (C) 2009 Elsevier Ireland Ltd. All rights reserved. Radiotherapy and Oncology 91 (2009) 455-460
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | GROSS TUMOR VOLUME; CONFORMAL RADIOTHERAPY; QUALITY-ASSURANCE; INTEROBSERVER VARIABILITY; RADIATION ONCOLOGISTS; DUMMY RUN; CT; DEFINITION; TRIAL; PET; Radiation therapy; Lung cancer; Interobserver variability; Delineation; Target volume |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Strahlentherapie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Sep 2020 09:38 |
| Last Modified: | 14 Sep 2020 09:38 |
| URI: | https://pred.uni-regensburg.de/id/eprint/28932 |
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