Bonjer, H. J. and Cuesta, M. A. and Lacy, A. M. and Haglind, E. and Fuerst, A. and Lange, J. F. and Hop, W. C. J. and Buunen, M. and D'Hoore, A. and Inglis, K. and Jess, P. and Bulut, O. and Rosenberg, J. and Peiman, and Christensen, M. Mark and Isalnieks, I. and Jaeger, C. and Kreis, M. and Jeekel, J. and van der Harst, E. and Coenen, P. P. L. O. and Gerhards, M. F. and Bemelman, W. and Jakimowicz, J. J. and van Riet, Y. E. A. and Hansson, B. M. E. and Rosman, C. and Neijenhuis, P. A. and den Outer, A. J. and Targarona, E. M. and Balague, C. and Delgado, S. and Lujan, J. and Garcia Molina, F. J. and Skullman, S. and Kurlberg, G. and Lackberg, Z. and Pahlman, L. and Kressner, U. and Matthiessen, P. and Kim, Seon-Hahn (2009) COLOR II - A randomized clinical trial comparing laparoscopic and open surgery for rectal cancer. DANISH MEDICAL BULLETIN, 56 (2). pp. 89-91. ISSN 0907-8916, 1603-9629
Full text not available from this repository. (Request a copy)Abstract
Introduction: Laparoscopic resection of rectal cancer has been proven efficacious but morbidity and oncological outcome need to be investigated in a randomized clinical trial. Trial design: Non-inferiority randomized clinical trial. Methods: The COLOR II trial is an ongoing international randomized clinical trial. Currently 27 hospitals from Europe, South Korea and Canada are including patients. The primary endpoint is loco-regional recurrence rate three years post-operatively. Secondary endpoints cover quality of life, overall and disease free survival, post-operative morbidity and health economy analysis. Results: By July 2008, 27 hospitals from the Netherlands, Belgium, Germany, Sweden, Spain, Denmark, South Korea and Canada had included 739 patients. The intra-operative conversion rate in the laparoscopic group was 17%. Distribution of age, location of the tumor and radiotherapy were equal in both treatment groups. Most tumors are located in the mid-rectum (41%). Conclusion: Laparoscopic surgery in the treatment of rectal cancer is feasible. The results and safety of laparoscopic surgery in the treatment of rectal cancer remain unknown, but are subject of interim analysis within the COLOR II trial. Completion of inclusion is expected by the end of 2009. Trial registration: Clinicaltrials.gov, identifier: NCT00297791 (www.clinicaltrials.gov).
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | OPEN COLECTOMY; RECURRENCE; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Chirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 16 Sep 2020 08:51 |
| Last Modified: | 16 Sep 2020 08:51 |
| URI: | https://pred.uni-regensburg.de/id/eprint/29032 |
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