Schreml, S. and Schroeder, J. and Eder, F. and Szeimies, R. M. and Landthaler, M. and Babilas, P. (2009) Hereditary and non-hereditary cutaneous amyloidoses. PATHOLOGE, 30 (3). pp. 197-204. ISSN 0172-8113, 1432-1963
Full text not available from this repository. (Request a copy)Abstract
Amyloid and amyloidosis describes a heterogenous group of diseases which are characterized by the pathological extracellular deposition of autologous proteins. Basically, amyloidoses can be divided into systemic or organ-limited (e.g. cutaneous) forms and can be acquired or hereditary in nature. The subclassification discriminates between primary amyloidosis (in the absence of an obvious predisposing disease) and secondary amyloidosis (if caused by a certain underlying disease). The subclassification of amyloidoses is based on the main protein constituent and therefore on the chemical composition of the amyloid fibrils. However, the exact etiopathogenesis of amyloid formation remains unclear. In addition to the clinical presentation, histology, electron microscopy and biochemical-immunological differentiation are also decisive for a proper diagnosis. In cutaneous amyloidosis the deposition of amyloid either occurs along reticulin fibers and the basal membrane (perireticulary amyloidoses) or along collagen fibers (pericollagenous amyloidosis). The purpose of this article is to provide an up-to-date overview on the different kinds of cutaneous amyloidoses.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SYSTEMIC AMYLOIDOSIS; NODULAR AMYLOIDOSIS; TRANSTHYRETIN; ASSOCIATION; MICROSCOPY; ELECTRON; FIBRILS; DISEASE; SKIN; Amyloidosis; Cutaneous; Hereditary; Non-hereditary; Skin signs |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Dermatologie und Venerologie Medicine > Lehrstuhl für Pathologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 17 Sep 2020 08:37 |
| Last Modified: | 17 Sep 2020 08:37 |
| URI: | https://pred.uni-regensburg.de/id/eprint/29091 |
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