Treatment of cluster headache in pregnancy and lactation

Juergens, T. P. and Schaefer, C. and May, A. (2009) Treatment of cluster headache in pregnancy and lactation. CEPHALALGIA, 29 (4). pp. 391-400. ISSN 0333-1024, 1468-2982

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Abstract

Cluster headache is a rare disorder in women, but has a serious impact on the affected woman's life, especially on family planning. Women with cluster headache who are pregnant need special support, including the expertise of an experienced headache centre, an experienced gynaecologist and possibly a teratology information centre. The patient should be seen through all stages of the pregnancy. A detailed briefing about the risks and safety of various treatment options is mandatory. In general, both the number of medications and the dosage should be kept as low as possible. Preferred treatments include oxygen, subcutaneous or intranasal sumatriptan for acute pain and verapamil and prednisone/prednisolone as preventatives. If there is a compelling reason to treat the patient with another preventative, gabapentin is the drug of choice. While breastfeeding, oxygen, sumatriptan and lidocaine for acute pain and prednisone/prednisolone, verapamil, and lithium as preventatives are the drugs of choice. As the individual pharmacokinetics differ substantially, adverse drug effects should be considered if unexplained symptoms occur in the newborn.

Item Type: Article
Uncontrolled Keywords: 1ST TRIMESTER EXPOSURE; OCCIPITAL NERVE-STIMULATION; BREAST-MILK; ANTIEPILEPTIC DRUGS; DEVELOPMENTAL TOXICITY; MATERNAL EXPOSURE; BIRTH-DEFECTS; BETA-BLOCKERS; ORAL CLEFTS; LITHIUM; Cluster headache; pregnancy; lactation; triptan; treatment
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Neurologie
Depositing User: Petra Gürster
Date Deposited: 10 Apr 2025 07:34
Last Modified: 10 Apr 2025 07:34
URI: https://pred.uni-regensburg.de/id/eprint/29151

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