Minimal Extracorporeal Circulation: An Alternative for On-Pump and Off-Pump Coronary Revascularization

Puehler, Thomas and Haneya, Assad and Philipp, Alois and Wiebe, Karsten and Keyser, Andreas and Rupprecht, Leopold and Hirt, Stephan and Kobuch, Reinhard and Diez, Claudius and Hilker, Michael and Schmid, Christof (2009) Minimal Extracorporeal Circulation: An Alternative for On-Pump and Off-Pump Coronary Revascularization. ANNALS OF THORACIC SURGERY, 87 (3). pp. 766-772. ISSN 0003-4975,

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Abstract

Background. Coronary artery bypass surgery employing minimal extracorporeal circulation (MECC) was compared with standard extracorporeal circulation (ECC) and off-pump coronary artery bypass graft surgery (OPCABG) with regard to the perioperative course. Methods. From January 2004 to December 2007, 1,674 patients (n = 558 MECC, n = 558 ECC, n = 558 OPCABG) who underwent coronary bypass surgery were studied. The primary end point was in-hospital mortality; secondary end points were perioperative variables, intensive care, and in-hospital course. Results. Demographic data, comorbidity, and the European System for Cardiac Operative Risk Evaluation score (MECC 3.0%, ECC 3.5%, OPCABG 3.2%) were similar among the groups, but in-hospital mortality for elective and urgent/emergent patients was lower in the MECC and OPCABG groups (MECC 3.2%, OPCABG 3.7%, ECC 6.9%; p < 0.05). The number of distal anastomoses was lowest in the OPCABG group, but comparable for MECC and ECC patients. Postoperative ventilation time, release of creatinine kinase, catecholamine therapy, drainage loss, and transfusion requirements were lower in the MECC and OPCABG groups, whereas stay in the intensive care unit was shorter only in the latter (p < 0.05). Conclusions. Minimal extracorporeal circulation is an easy and safe procedure for coronary artery bypass graft surgery. In selected patients, the advantages of MECC equal those of OPCABG. MECC should be considered as an alternative to OPCABG and standard ECC procedures.

Item Type: Article
Uncontrolled Keywords: BYPASS GRAFT-SURGERY; CARDIOPULMONARY BYPASS; INFLAMMATORY RESPONSE; FOLLOW-UP; CIRCUIT; EXPERIENCE; OUTCOMES; PATENCY; SYSTEM;
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 21 Sep 2020 09:17
Last Modified: 21 Sep 2020 09:17
URI: https://pred.uni-regensburg.de/id/eprint/29304

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