Vogel, P. and Bolder, U. and Scherer, M. N. and Schlitt, H. -J. and Jauch, K. -W. (2009) Long-term outcome after multivisceral and tumor/vascular resection in patients with soft tissue sarcoma. LANGENBECKS ARCHIVES OF SURGERY, 394 (2). pp. 331-337. ISSN 1435-2443,
Full text not available from this repository. (Request a copy)Abstract
Soft tissue sarcomas (STS) are rare tumors. General treatment is difficult while multimodality treatment strategies are more and more common. In these strategies, surgical resection of the primary tumor is essential to achieve local control of the tumor. In certain cases, complex resections (CR) including multivisceral and/or vascular resection are needed to achieve resection with tumor-free margins. In this study, we evaluated retrospectively the overall prognosis, morbidity, and mortality of patients treated for STS at our university hospital. Between 1992 and 2000, 24 of 154 patients with STS received multivisceral resection and four of 154 underwent vascular resection. To determine the influence of CR on overall prognosis, we compared n = 19 patients after CR with a matched control group after simple tumor resection (SR). To determine surgical morbidity and mortality the whole study group was used (n = 154, SR n = 126, CR n = 28). The median follow up for all patients was 6.89 years (mean 5.64 years SD 4.3) with no difference between the groups (CR vs SR: 5.4 SD 4.8 vs 5.9 SD 3.9 years; p = 0.711). Patients receiving CR had a similar overall prognosis (mean survival 9.9 years), morbidity (10.7%) and mortality (0%) compared to patients with SR (mean survival 8.5 years; morbidity 10.3%; mortality 3.96%). Multivisceral resection and/or vascular resection with tumor-free margins can be achieved with the same overall prognosis, same morbidity and mortality as SR. This has to be taken into account when evaluating the treatment strategy in patients with STS.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | RETROPERITONEAL SARCOMAS; VASCULAR RECONSTRUCTION; PROGNOSTIC FACTORS; LOWER-EXTREMITY; SURGERY; MANAGEMENT; MARGIN; TUMORS; Soft tissue sarcoma; Multivisceral resection; Tumor and vascular resection; Multimodality treatment; Long-term outcome; Overall prognosis |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Chirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 05 Oct 2020 06:07 |
| Last Modified: | 05 Oct 2020 06:07 |
| URI: | https://pred.uni-regensburg.de/id/eprint/29413 |
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