Bala, Margarita and Bollheimer, Cornelius and Schoelmerich, Juergen and Schaeffler, Andreas (2009) Hormone-Induced Spontaneous Femoral Neck Fracture in a 28-Year-Old Female Patient. MEDIZINISCHE KLINIK, 104 (3). pp. 244-248. ISSN 0723-5003, 1615-6722
Full text not available from this repository. (Request a copy)Abstract
A 28-year-old woman was referred to hospital with a spontaneous femoral neck fracture. Dual energy X-ray absorptiometry showed severe osteoporosis without apparent cause or risk factors. The basic endocrinologic evaluation revealed hypercortisolism, and the diagnosis of Cushing's disease could be made following biochemical test and magnetic resonance imaging. A transsphenoidal resection of the pituitary gland tumor was performed and led to a cure of the disease. The patient received calcium and vitamin D substitution as well as biphosphonates. Glucocorticoid-induced osteoporosis is the most frequent cause of secondary osteoporosis. Only few cases with occult endogenous Cushing's syndrome and osteoporosis as the main manifestation of the disease have been reported. Nevertheless, hypercortisolism should be excluded whenever osteoporosis without apparent cause is diagnosed.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | GLUCOCORTICOID-INDUCED OSTEOPOROSIS; CUSHINGS-DISEASE; ADULT PATIENTS; BONE MASS; TURNOVER; Cushing's disease; Osteoporosis; Femoral neck fracture |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin I |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 05 Oct 2020 06:11 |
| Last Modified: | 05 Oct 2020 06:11 |
| URI: | https://pred.uni-regensburg.de/id/eprint/29415 |
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