Tregouet, David-Alexandre and Koenig, Inke R. and Erdmann, Jeanette and Munteanu, Alexandru and Braund, Peter S. and Hall, Alistair S. and Grosshennig, Anika and Linsel-Nitschke, Patrick and Perret, Claire and DeSuremain, Maylis and Meitinger, Thomas and Wright, Ben J. and Preuss, Michael and Balmforth, Anthony J. and Ball, Stephen G. and Meisinger, Christa and Germain, Cecile and Evans, Alun and Arveiler, Dominique and Luc, Gerald and Ruidavets, Jean-Bernard and Morrison, Caroline and van der Harst, Pim and Schreiber, Stefan and Neureuther, Katharina and Schaefer, Arne and Bugert, Peter and El Mokhtari, Nour E. and Schrezenmeir, Juergen and Stark, Klaus and Rubin, Diana and Wichmann, H-Erich and Hengstenberg, Christian and Ouwehand, Willem and Ziegler, Andreas and Tiret, Laurence and Thompson, John R. and Cambien, Francois and Schunkert, Heribert and Samani, Nilesh J. (2009) Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. NATURE GENETICS, 41 (3). pp. 283-285. ISSN 1061-4036,
Full text not available from this repository. (Request a copy)Abstract
We identify the SLC22A3-LPAL2-LPA gene cluster as a strong susceptibility locus for coronary artery disease (CAD) through a genome-wide haplotype association (GWHA) study. This locus was not identified from previous genome-wide association (GWA) studies focused on univariate analyses of SNPs. The proposed approach may have wide utility for analyzing GWA data for other complex traits.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | APOLIPOPROTEIN(A) GENE; MYOCARDIAL-INFARCTION; LIPOPROTEIN(A) LEVELS; HEART-DISEASE; POLYMORPHISMS; ECTIM; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin II |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 05 Oct 2020 06:45 |
| Last Modified: | 05 Oct 2020 06:45 |
| URI: | https://pred.uni-regensburg.de/id/eprint/29423 |
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