Pumpless extracorporeal removal of carbon dioxide combined with ventilation using low tidal volume and high positive end-expiratory pressure in a patient with severe acute respiratory distress syndrome

Bein, Thomas and Zimmermann, M. and Hergeth, K. and Ramming, M. and Rupprecht, L. and Schlitt, H. J. and Slutsky, A. S. (2009) Pumpless extracorporeal removal of carbon dioxide combined with ventilation using low tidal volume and high positive end-expiratory pressure in a patient with severe acute respiratory distress syndrome. ANAESTHESIA, 64 (2). pp. 195-198. ISSN 0003-2409,

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Abstract

The effects of the combination of a 'lowest' lung ventilation with extracorporeal elimination of carbon dioxide by interventional lung assist are described in a patient presenting with severe acute respiratory distress syndrome due to fulminant pneumonia. Reducing tidal volume to 3 ml.kg(-1) together with interventional lung assist resulted in a decrease in severe hypercapnia without alveolar collapse or hypoxaemia but with a decrease in serum levels of interleukin-6. This approach was applied for 12 days with recovery of the patient, without complications. Extracorporeal removal of carbon dioxide by interventional lung assist may be a useful tool to enable 'ultraprotective' ventilation in severe acute respiratory distress syndrome.

Item Type: Article
Uncontrolled Keywords: ACUTE LUNG INJURY; MECHANICAL VENTILATION; FAILURE; INFLAMMATION; ASSIST; TRIAL; MODEL; CO2;
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Anästhesiologie
Medicine > Lehrstuhl für Chirurgie
Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 05 Oct 2020 12:55
Last Modified: 05 Oct 2020 12:55
URI: https://pred.uni-regensburg.de/id/eprint/29482

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