Zuber-Jerger, Ina and Endlicher, Esther and Kullmann, Frank and Gelbmann, Cornelia M. (2009) A new grading system to evaluate the risk of endoscopic retrograde cholangiopancreatography. JOURNAL OF GASTROENTEROLOGY, 44 (2). pp. 160-165. ISSN 0944-1174,
Full text not available from this repository.Abstract
The aim of our study was to develop a system to grade the risk of the procedures summarized under the term endoscopic retrograde cholangiopancreatography (ERCP). In a controlled prospective study, we evaluated the early complications of ERCP in 526 consecutive patients at a single endoscopy center in a defined period. The relation between endoscopic procedures and related complications was analyzed for significance. A grading system based on significant risk factors and clinical implications was developed. Of the ERCP procedures, 29% were diagnostic and 71% therapeutic. A total of 45 complications occurred in 42 patients: pancreatitis (2%), perforation (1%), cardiorespiratory problems (0.6%), stent-related complications (0.5%), leakages (1.5%), and bleeding (3%). A native papilla was a significant risk factor for the development of complications (P = 0.046). On the basis of these findings, we defined five groups of ERCP-related complications: nonnative papillae with either diagnostic (A) or therapeutic interventions (B); native papillae with diagnostic (C) or therapeutic (D) interventions; and special therapeutic interventions (E). Complication rates differed significantly between individual groups, A versus D (P = 0.013), A versus E (P = 0.010), B versus D (P = 0.005), and B versus E (P = 0.003), as well as between A/B and C/D (P = 0.003). A grading system based on differentiating between native and nonnative papillae and diagnostic versus therapeutic procedures demonstrated significantly different complication rates. This grading system has the potential to predict the risk of ERCP-related complications.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PROSPECTIVE MULTICENTER; EARLY COMPLICATIONS; THERAPEUTIC ERCP; SPHINCTEROTOMY; endoscopic retrograde cholangiopancreatography (ERCP); complication; grading systems; risk |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin I |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 07 Oct 2020 06:03 |
| Last Modified: | 07 Oct 2020 06:03 |
| URI: | https://pred.uni-regensburg.de/id/eprint/29528 |
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