Mehrotra, R. and Hullmann, M. and Smeets, R. and Reichert, T. E. and Driemel, O. (2009) Oral cytology revisited. JOURNAL OF ORAL PATHOLOGY & MEDICINE, 38 (2). pp. 161-166. ISSN 0904-2512, 1600-0714
Full text not available from this repository. (Request a copy)Abstract
During the last decade, oral cytology has once again become the focus of scientific research. This new interest is due to the introduction of a cytobrush for cell collection as well as a computer-assisted analysis (Oral CDx((R))). Although promising, the sensitivity and specificity of conventional oral brush cytology remains limited. To circumvent the problems and improve the accuracy, various adjunctive analytical methods have been attempted. DNA analysis, immunocytochemical and molecular analysis are suggested methodological cytology approaches to improve the validity of oral brush cytology. An increase in sensitivity (up to 100%) and specificity (up to 100%) of oral brush biopsy has been reported on localized pre-malignant and malignant lesions. Oral brush biopsy probably will not replace histopathology in the definitive diagnosis of oral cancer, but it might be valuable for the prevention of misdiagnosis of clinically doubtful oral lesions and for the monitoring of lesions that might proceed on to oral cancer.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SQUAMOUS-CELL CARCINOMA; COMPUTER-ASSISTED ANALYSIS; EXFOLIATIVE CYTOLOGY; BRUSH BIOPSIES; EARLY-DIAGNOSIS; SUSPICIOUS LESIONS; SMEAR QUALITY; CANCER; CAVITY; CYTOBRUSH; oral brush biopsy; oral cancer; oral cytology; oral smear; precursor lesions |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Mund-, Kiefer- und Gesichtschirurgie |
| Depositing User: | Petra Gürster |
| Date Deposited: | 20 Oct 2022 11:20 |
| Last Modified: | 20 Oct 2022 11:20 |
| URI: | https://pred.uni-regensburg.de/id/eprint/29532 |
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