Schumacher, Axel and Friedrich, Patricia and Diehl, Janine and Ibach, Bernd and Schoepfer-Wendels, Andreas and Mueller, Jakob C. and Konta, Lidija and Laws, Simon M. and Kurz, Alexander and Foerstl, Hans and Riemenschneider, Matthias (2009) No association of common VCP variants with sporadic frontotemporal dementia. NEUROBIOLOGY OF AGING, 30 (2). pp. 333-335. ISSN 0197-4580, 1558-1497
Full text not available from this repository. (Request a copy)Abstract
Mutations in the gene for valosin containing protein (VCP) cause autosomal dominant inclusion body myopathy associated with Paget disease and frontotemporal dementia (IBMPFD). To investigate the role of this novel gene in sporadic forms of frontotemporal dementia (FTD). we genotyped 27 single nucleotide polymorphisms covering the entire VCP genomic region in 198 patients with sporadic FTD and 184 matched controls from Germany. No significant association could be demonstrated. There is no evidence, that common variants in VCP confer a strong risk to the development of sporadic FTD. (C) 2007 Elsevier Inc. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | VALOSIN-CONTAINING-PROTEIN; INCLUSION-BODY MYOPATHY; GENE-MUTATIONS; PAGET-DISEASE; Genetic association study; Valosin containing protein; VCP; Frontotemporal dementia; FTD; FANGC; PIGO |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Psychiatrie und Psychotherapie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 07 Oct 2020 07:04 |
| Last Modified: | 07 Oct 2020 07:04 |
| URI: | https://pred.uni-regensburg.de/id/eprint/29545 |
Actions (login required)
 |
View Item |
