Geis, S. and Schreml, S. and Lamby, P. and Obed, A. and Jung, E. M. and Nerlich, M. and Babilas, P. and Szeimies, R. -M. and Prantl, Lukas (2009) Postoperative assessment of free skin flap viability by transcutaneous pO(2) measurement using dynamic phosphorescence imaging. CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 43 (1-2). pp. 11-18. ISSN 1386-0291,
Full text not available from this repository. (Request a copy)Abstract
Background: Free flap transplantation is used more and more frequently in order to cover extensive wound defects. The basic prerequisite for successful flap salvage after flap failure is a short time interval from failure until revision. For this reason many different flap monitoring systems have been tested over the last years. But none of them has made the way into clinical routine. Objective: The aim of this clinical study was to study whether luminescence lifetime imaging (LLI) is an adequate method to assess flap viability during the postoperative period. In previous experiments LLI was proven to be a precise and non-invasive monitoring system for transcutaneous oxygen measurement. Methods: p(tc)O(2) of 9 patients was detected during a postoperative period of 72 hours. In all cases the transplantation was performed by the same experienced surgeon. During the first 4 hours almost constant p(tc)O(2) values were detected (53 +/- 0.7 mmHg). During the following time intervals p(tc)O(2) values decreased and reached a more or less constant level after approximately 12 hours. The mean p(tc)O(2) decreased from 53 +/- 0.7 mmHg to 39 +/- 1.0 mmHg. In one case an immediate decrease of p(tc)O(2) below 10 mmHg was observed and a subsequently intervention was necessary to improve flap perfusion. Conclusion: In this clinical trial, perfusion dynamics after free flap transplantation as well as the detection of vascular complications were demonstrated using LLI. Based on these data, LLI seems to be a sensitive and adequate monitoring system for the evaluation of free flap viability.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | FREE-TISSUE TRANSFER; INDOCYANINE GREEN; OPTICAL SENSORS; OXYGEN SENSORS; MODEL; FLUORESCENCE; ULTRASOUND; EXPERIENCE; HEAD; PH; Oxygen; free flaps; luminescence lifetime imaging |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Dermatologie und Venerologie Medicine > Lehrstuhl für Röntgendiagnostik Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Plastische-, Hand- und Wiederherstellungschirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 12 Oct 2020 06:44 |
| Last Modified: | 12 Oct 2020 06:44 |
| URI: | https://pred.uni-regensburg.de/id/eprint/29679 |
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