Ehrenstein, B. and Reischl, U. (2016) PCR-based detection of pathogens in clinical rheumatology. ZEITSCHRIFT FUR RHEUMATOLOGIE, 75 (4). pp. 381-387. ISSN 0340-1855, 1435-1250
Full text not available from this repository. (Request a copy)Abstract
In the differential diagnostics of autoimmune-mediated rheumatic diseases, rheumatologists often have to consider infections (e. g. Lyme arthritis) or reactive diseases (e. g. reactive arthritis after urogenital bacterial infections). Furthermore, infections with an atypical presentation or caused by atypical pathogens (opportunistic infections) can complicate the immunosuppressive therapy of autoimmune diseases. For this purpose not only conventional microbiological culture methods but also PCR-based methods are increasingly being applied for the direct detection of pathogens in clinical specimens. The aim of this overview is to present commonly used PCR methods in the clinical practice of rheumatology and to describe their benefits and limitations compared to culture-based detection methods.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | POLYMERASE-CHAIN-REACTION; WHIPPLES-DISEASE; REACTIVE ARTHRITIS; PNEUMOCYSTIS PNEUMONIA; DOUBLE-BLIND; DIAGNOSIS; IDENTIFICATION; DNA; CHLAMYDIA; INFECTION; Borreliosis; Lyme arthritis; Reactive arthritis; Infection; Immunosuppression |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Orthopädie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 25 Mar 2019 10:38 |
| Last Modified: | 25 Mar 2019 10:38 |
| URI: | https://pred.uni-regensburg.de/id/eprint/2990 |
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