Mengel, Anne and Reiser, Oliver and Aube, Jeffrey (2008) Synthesis and structural study of cyclic 5-aminovaleric acid-linked beta-Ala-beta-Ala dipeptides. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 18 (22). pp. 5975-5977. ISSN 0960-894X,
Full text not available from this repository. (Request a copy)Abstract
5-Aminovaleric acid and ornithine were evaluated as linkers for the cyclization of beta-dipeptides. Two linked examples of beta-Ala-beta-Ala were prepared by standard coupling methods and their conformations probed by NMR, CD, and computational means. The data suggest that these non- or monosubstituted versions of the target compounds are flexible in solution. (C) 2008 Elsevier Ltd. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CONFORMATIONAL FREE-ENERGIES; CHAIN REVERSALS; MODEL PEPTIDES; AMINO-ACIDS; TURN MIMICS; CYS-NHME; BEND; CYCLO(L-ALANYLGLYCYL-EPSILONAMINOCAPROYL); CYCLIZATION; PROTEINS; beta-Peptide; Cyclic peptide; Peptidomimetics |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Organische Chemie Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Oliver Reiser |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 19 Oct 2020 05:48 |
| Last Modified: | 19 Oct 2020 05:48 |
| URI: | https://pred.uni-regensburg.de/id/eprint/30050 |
Actions (login required)
 |
View Item |
