Besch, D. and Sachs, H. and Szurman, P. and Guelicher, D. and Wilke, R. and Reinert, S. and Zrenner, E. and Bartz-Schmidt, K. U. and Gekeler, F. (2008) Extraocular surgery for implantation of an active subretinal visual prosthesis with external connections: feasibility and outcome in seven patients. BRITISH JOURNAL OF OPHTHALMOLOGY, 92 (10). pp. 1361-1368. ISSN 0007-1161,
Full text not available from this repository. (Request a copy)Abstract
Background: Due to low energy levels in microphotodiode-based subretinal visual prostheses, an external power supply is mandatory. We report on the surgical feasibility and the functional outcome of the extraocular part of an approach to connect a subretinal prosthesis to an extracorporeal connector in the retro-auricular space via a trans-scleral, transchoroidal cable. Methods: Seven volunteers with retinitis pigmentosa received an active subretinal implant; energy was supplied by gold wires on a trans-sclerally, transchoroidally implanted polyimide foil leading to the lateral orbital rim where it was fixated and connected to a silicone cable. The cable was implanted subperiostally beneath the temporal muscle using a trocar to the retro-auricular space where it penetrated the skin for connection to a stimulator. To avoid subretinal movement of the implant, three tension relief points have been introduced. Results: All implantations were performed as planned without complications, and no serious adverse events occurred in the postoperative period. Fixation of the implants was stable throughout the entire study duration of 4 weeks; permanent skin penetration proved to be uncomplicated. Motility was minimally restricted in downgaze and ab-/adduction. Explantation was uneventful. Conclusion: The above-described procedure provides a method for stable fixation of a subretinal device with a trans-scleral, transchoroidal cable connection to an extracorporeal connector.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | RETINITIS-PIGMENTOSA; DEGENERATED PHOTORECEPTORS; MORPHOMETRIC ANALYSIS; RETINAL PROSTHESIS; RESTORE VISION; RABBIT RETINA; STIMULATION; ELECTRODES; MICROPHOTODIODES; ARRAYS; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Augenheilkunde |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 22 Oct 2020 08:23 |
| Last Modified: | 22 Oct 2020 08:23 |
| URI: | https://pred.uni-regensburg.de/id/eprint/30197 |
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