Rau, T. T. and Hartmann, A. and Dietmaier, W. and Schmitz, J. and Hohenberger, W. and Hofstaedter, F. and Katenkamp, K. (2008) Plexiform angiomyxoid myofibroblastic tumour: differential diagnosis of gastrointestinal stromal tumour in the stomach. JOURNAL OF CLINICAL PATHOLOGY, 61 (10). pp. 1136-1137. ISSN 0021-9746,
Full text not available from this repository. (Request a copy)Abstract
Mesenchymal tumours other than gastrointestinal stromal tumours are rare in the stomach. Nevertheless it is important to incorporate them into the differential diagnosis. Plexiform angiomyxoid myofibroblastic tumour is a recently described new entity of a presumably benign mesenchymal gastric tumour. This report presents what is believed to be the third case of this tumour. The tumour is characterised by bland spindle cells in a plexiform pattern, a mucinous extracellular matrix and a network of thin blood vessels. These findings are completely in line with the two previous reported cases. There was a strong positivity for alpha-smooth muscle actin and a low proliferation index (< 2%). The tumour had no C-KIT or CD34 expression and no mutation in the C-KIT and PDFGR alpha genes. Plexiform angiomyxoid myofibroblastic tumour may present a new mesenchymal tumour entity in the stomach.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | C-KIT; MUTATIONS; GIST; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Pathologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 22 Oct 2020 11:44 |
| Last Modified: | 22 Oct 2020 11:44 |
| URI: | https://pred.uni-regensburg.de/id/eprint/30228 |
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