Judex, Antonia and Hartung, Wolfgang and Schoelmerich, Juergen and Fleck, Martin (2008) Hypothyroidism with Leading Myopathy in a Patient Suffering from Systemic Lupus Erythematosus and Hashimoto's Thyroiditis. MEDIZINISCHE KLINIK, 103 (10). pp. 731-735. ISSN 0723-5003,
Full text not available from this repository. (Request a copy)Abstract
Background:Muscle weakness with or without elevation of serum cre atine kinase (CK) is a common complaint, which is a diagnostic challenge for the treating physician. Either infectious, neurologic, iatrogenic, genetic or endocrinologic and rheumatologic causes should be considered. Case Report: A 66-year-old female patient with a history of systemic lupus erythematosus (SLE) currently in remission presented herself with muscle weakness, myalgias and elevated CK (1,618 U/l) to the authors' hospital. A flare of the SLE as cause of the symptoms could be ruled out diagnostically. Instead, a Hashimoto's-associated hypothyroidism was detected. Treatment with L-thyroxine resulted in rapid improvement of symptoms, and CK levels returned to normal. Conclusion: Although a myositis can be observed in SLE patients suffering from muscle weakness with elevated CK levels, a careful evaluation is warranted. In the presented case, hypothyroidism due to Hashimoto's thyroiditis was the real culprit of the symptoms.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SUBCLINICAL HYPOTHYROIDISM; DYSFUNCTION; DISEASE; SLE; Hashimoto's thyroiditis; Hypothyroidism; Myalgias; Muscle weakness |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin I |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 23 Oct 2020 07:00 |
| Last Modified: | 23 Oct 2020 07:00 |
| URI: | https://pred.uni-regensburg.de/id/eprint/30241 |
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