Langguth, B. and Eichhammer, P. and Zowe, M. and Landgrebe, M. and Binder, H. and Sanda, P. and Hajak, G. (2008) Modulating cerebello-thalamocortical pathways by neuronavigated cerebellar repetitive transcranial stimulation (rTMS). NEUROPHYSIOLOGIE CLINIQUE-CLINICAL NEUROPHYSIOLOGY, 38 (5). pp. 289-295. ISSN 0987-7053,
Full text not available from this repository. (Request a copy)Abstract
Objectives. -Increasing evidence suggests that dysfunctions of the cortico-cerebello-thalamocortical circuit are involved in the pathophysiology of neuropsychiatric disorders. This study explores the effects of cerebellar repetitive transcranial magnetic stimulation (rTMS) on cerebetto-thalamocortical pathways. Methods. -Ten healthy volunteers received MRI-guided rTMS in four separate sessions (120% motor threshold, 1000 stimuli) over either the medial or the right lateral cerebellum using frequencies of 1 and 10 Hz. Motor cortex excitability was assessed before and after the intervention by paired-pulse transcranial magnetic stimulation. Results. -Depending on stimulation frequency, cerebellar rTMS differentially modified intracortical inhibition. Low frequency rTMS increased short intracortical inhibition (SICI), whereas high frequency rTMS had no significant effect on SICI. Conclusions. -These results suggest that rTMS over the cerebellum can modulate cerebello-thalamocortical, pathways in a frequency-specific manner. (c) 2008 Elsevier Masson SAS. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MOTOR CORTEX EXCITABILITY; MAGNETIC STIMULATION; HUMANS; COGNITION; Repetitive transcranial magnetic stimulation; Paired pulse transcranial magnetic stimulation; Cerebellum; Cortical excitability; Cerebello-thalamocortical circuit |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Psychiatrie und Psychotherapie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 23 Oct 2020 07:05 |
| Last Modified: | 23 Oct 2020 07:05 |
| URI: | https://pred.uni-regensburg.de/id/eprint/30250 |
Actions (login required)
 |
View Item |
