Agha, Ayman and Fuerst, Alois and Hierl, Johanna and Iesalnieks, Igors and Glockzin, Gabriel and Anthuber, Matthias and Jauch, Karl-Walter and Schlitt, Hans J. (2008) Laparoscopic surgery for rectal cancer: oncological results and clinical outcome of 225 patients. SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 22 (10). pp. 2229-2237. ISSN 0930-2794,
Full text not available from this repository. (Request a copy)Abstract
Introduction The efficacy and feasibility of laparoscopic resection for rectal cancer has been proved, but the results of prospective, randomized studies are not yet available. Here we present a prospective observational study evaluating oncological and clinical outcome after laparoscopic surgery in patients with rectal cancer. Patients and Methods Between January 1998 and March 2005, 225 patients with rectal adenocarcinoma underwent laparoscopic surgery at the University of Regensburg Medical Center. Clinical and oncological outcome of these patients including perioperative and long-term complications was evaluated. Survival curves were calculated according to the Kaplan-Meier method. Minimum follow-up was 24 months. Results The distribution of the International Union against Cancer ( UICC) stages was: 37.7% stage I, 20.5% stage II, 24.9% stage III, and 16.9% stage IV. Local recurrence was diagnosed in 5.8% and distant metastases in 8.1% of cases after mean follow-up of 36.4 months. The 5-year overall survival rate was 75.7% after curative and 40.7% after palliative surgery (p < 0.05). The stage-related survival rates were 86.7% for UICC stage I, 61.7% for stage II, 68.1% for stage III, and 40.1% for stage IV. Conclusions Our results demonstrate the efficacy and technical feasibility of laparoscopic surgery for rectal cancer regarding the perioperative morbidity and the oncological outcome.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | TOTAL MESORECTAL EXCISION; LONG-TERM OUTCOMES; MRC CLASICC TRIAL; COLORECTAL SURGERY; ABDOMINOPERINEAL RESECTION; RANDOMIZED-TRIAL; OPEN COLECTOMY; ANTERIOR RESECTION; ASSISTED COLECTOMY; COLON-CANCER; Laparoscopic rectal surgery; Rectal cancer; Oncological outcome; Survival; Complication rate |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Chirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 26 Oct 2020 05:45 |
| Last Modified: | 26 Oct 2020 05:45 |
| URI: | https://pred.uni-regensburg.de/id/eprint/30260 |
Actions (login required)
 |
View Item |
