Vlachy, N. and Merle, C. and Touraud, D. and Schmidt, J. and Talmon, Y. and Heilmann, J. and Kunz, Werner (2008) Spontaneous formation of Bilayers and vesicles in mixtures of single-chain alkyl carboxylates: Effect of pH and aging and cytotoxicity studies. LANGMUIR, 24 (18). pp. 9983-9988. ISSN 0743-7463,
Full text not available from this repository.Abstract
We report the observation of bilayer fragments, some of which close to form vesicles, over a large range of pH at room temperature from mixtures of single-chain biocompatible commercially available nontoxic alkyl carboxylic surfactants after neutralization with HCl. The pH at which the morphological transitions occur is varied only by changing the ratio between two surfactants: the alkyloligoethyleneoxide carboxylate and sodium laurate. The effect of aging of the mixed surfactant systems in the pH region desired for dermatologic application (4.5 < pH < 7) is also studied. Finally, we show results of cytotoxicity studies on the surfactant mixtures.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | DEPENDENT AGGREGATION BEHAVIOR; DENSELY PACKED MONODISPERSE; SENSITIVE LIPOSOMES; AQUEOUS MIXTURES; PHASE-BEHAVIOR; UNILAMELLAR VESICLES; GEL PHASE; SURFACTANTS; DELIVERY; MICELLE; |
| Subjects: | 500 Science > 540 Chemistry & allied sciences 600 Technology > 615 Pharmacy |
| Divisions: | Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Biology (Prof. Heilmann) Chemistry and Pharmacy > Institut für Physikalische und Theoretische Chemie > Chair of Chemistry VI - Physical Chemistry (Solution Chemistry) > Prof. Dr. Werner Kunz |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 26 Oct 2020 06:32 |
| Last Modified: | 26 Oct 2020 06:32 |
| URI: | https://pred.uni-regensburg.de/id/eprint/30279 |
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