Leiberich, P. and Nickel, M. K. and Tritt, K. and Gil, F. Pedrosa (2008) Lamotrigine treatment of aggression in female borderline patients, Part II: an 18-month follow-up. JOURNAL OF PSYCHOPHARMACOLOGY, 22 (7). pp. 805-808. ISSN 0269-8811,
Full text not available from this repository. (Request a copy)Abstract
Borderline patients often display pathological aggression. We previously tested lamotrigine, an anti-convulsant, in therapy for aggression in women with borderline personality disorder (BPD) (J Psychopharmacol 2005; 19: 287-291), and found significant changes on most scales of the State-Trait Anger Expression Inventory (STAXI) after eight weeks. To assess the longer-term efficacy of lamotrigine in therapy for aggression in women with BPD, this 18-month follow-up observation was carried out, in which patients (treated with lamotrigine: n = 18; former placebo group: n = 9) were tested every six months. According to the intent-to-treat principle, significant changes on all scales of the STAXI were observed in the lamotrigine-treated subjects. All subjects tolerated lamotrigine relatively well. Lamotrigine appears to be an effective and relatively safe agent in the longer-term treatment of aggression in women with BPD.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PERSONALITY-DISORDER; DOUBLE-BLIND; TOPIRAMATE TREATMENT; CARBAMAZEPINE; AGITATION; TRIAL; borderline personality disorder; aggression; lamotrigine |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Abteilung für Psychosomatische Medizin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 26 Oct 2020 09:30 |
| Last Modified: | 26 Oct 2020 09:30 |
| URI: | https://pred.uni-regensburg.de/id/eprint/30396 |
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