Juergens, T. P. and Busch, V. and Opatz, O. and Schulte-Mattler, W. J. and May, A. (2008) Low-frequency short-time nociceptive stimulation of the greater occipital nerve does not modulate the trigeminal system. CEPHALALGIA, 28 (8). pp. 842-846. ISSN 0333-1024,
Full text not available from this repository. (Request a copy)Abstract
Occipital stimulation in a small group of refractory chronic migraine and cluster headache patients has been suggested as a novel therapeutic approach with promising results. In an earlier study we have shown that a drug-induced block of the greater occipital nerve (GON) inhibits the nociceptive blink reflex (nBR). Now, we sought to examine the effects of low-frequency (3 Hz) short-time nociceptive stimulation of the GON on the trigeminal system. We recorded the nBR responses before and after stimulation in 34 healthy subjects. Selectivity of GON stimulation was confirmed by eliciting somatosensory evoked potentials of the GON upon stimulation. In contrast to an anaesthetic block of the occipital nerve, no significant changes of the R2-latencies and R2-response areas of the nBR can be elicited following GON stimulation. Various modes of electrical stimulation exist with differences in frequency, stimulus intensity, duration of stimulation and pulse width. One explanation for a missing modulatory effect in our study is the relatively short duration of the stimulation.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | HUMAN BLINK REFLEX; CHRONIC CLUSTER HEADACHE; FUNCTIONAL CONNECTIVITY; CUTANEOUS ALLODYNIA; MIGRAINE; BLOCKADE; AFFERENT; NEURONS; FIBERS; PAIN; electrical stimulation; functional connectivity; greater occipital nerve; nociceptive blink reflex; occipital nerve stimulation; trigeminal nerve |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Neurologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 26 Oct 2020 15:36 |
| Last Modified: | 26 Oct 2020 15:36 |
| URI: | https://pred.uni-regensburg.de/id/eprint/30503 |
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