Gamulescu, Maria-Andreea and Walter, Andreas and Sachs, Helmut and Helbig, Horst (2008) Bevacizumab in the treatment of idiopathic macular telangiectasia. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 246 (8). pp. 1189-1193. ISSN 0721-832X,
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Background To describe functional and morphological long-term follow-up results in patients with idiopathic macular telangiectasia (IMT) treated with intravitreal bevacizumab. Methods Retrospective case series of three consecutive male patients with IMT who were treated with intravitreal bevacizumab injections. Best corrected visual acuity (BCVA) as well as fluorescein angiography (FA) and optical coherence tomography (OCT) were monitored over the period of up to 12 months. Results Single intravitreal bevacizumab injection resulted in a marked increase in BCVA from 20/50 to 20/20 in the patient with type 1 (aneurysmal) IMT during the first 4 weeks. Late-phase leakage on FA and cystoid macular oedema on OCT decreased significantly. This was sustained over the whole follow-up period of 12 months. In contrast, in the two patients with type 2 (perifoveal) IMT, leakage on FA decreased likewise, but this was not accompanied by an increase in BCVA despite triple injections. Small cystic changes seen on OCT remained unchanged. Conclusion Patients with type 1 IMT with pronounced macular oedema on OCT may benefit from intravitreal bevacizumab injections, showing functional as well as morphological improvement, while patients with type 2 IMT with minimal cystic changes on OCT do not show functional improvement despite repeated injections.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | JUXTAFOVEOLAR RETINAL TELANGIECTASIS; OPTICAL COHERENCE TOMOGRAPHY; INTRAVITREAL TRIAMCINOLONE; EDEMA; idiopathic macular telangiectasia; idiopathic juxtafoveal retinal telangiectasia; bevacizumab; avastin (R); treatment |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Augenheilkunde |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 26 Oct 2020 11:01 |
| Last Modified: | 26 Oct 2020 11:01 |
| URI: | https://pred.uni-regensburg.de/id/eprint/30529 |
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