Facile access to 2-arylindolines and 2-arylindoles by microwave-assisted tandem radical cyclization

Prediger, Inga and Weiss, Torsten and Reiser, Oliver (2008) Facile access to 2-arylindolines and 2-arylindoles by microwave-assisted tandem radical cyclization. SYNTHESIS-STUTTGART (14). pp. 2191-2198. ISSN 0039-7881,

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Abstract

A new route providing access to 2-arylindoles has been developed. The synthesis consists of a tin-mediated tandem radical cyclization of appropriate precursors to form 2,3-disubstituted dihydroindoles, which in turn are oxidized to yield the corresponding 2-arylindoles. The reactions proceed smoothly under microwave irradiation, furnishing the desired products in good yields.

Item Type: Article
Uncontrolled Keywords: 2,3-DISUBSTITUTED INDOLES; ALPHA; LIGANDS; SYSTEMS; 2-ARYL; indoles; cyclizations; heterocycles; radical reactions; dehydrogenations; microwave irradiation
Subjects: 500 Science > 540 Chemistry & allied sciences
Divisions: Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Oliver Reiser
Depositing User: Dr. Gernot Deinzer
Date Deposited: 28 Oct 2020 08:03
Last Modified: 28 Oct 2020 08:03
URI: https://pred.uni-regensburg.de/id/eprint/30613

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