Klein, S. M. and Prantl, L. and Berner, A. and Schreml, S. and Schubert, T. and Rennert, J. and Fellner, C. and Stopfer, A. and Angele, P. and Schreyer, A. G. and Schreyer, C. I. and Feuerbach, S. and Jung, E. M. (2008) A new method to quantify the effect after subcutaneous injection of lipolytic substances. AESTHETIC PLASTIC SURGERY, 32 (4). pp. 667-672. ISSN 0364-216X,
Full text not available from this repository. (Request a copy)Abstract
Background Increasing numbers of patients request lipolytic injection therapy for aesthetic indications. However, only the clinical results of these therapies have been published to date. In most cases, pre- and postprocedure photographs and measurements have been presented. As with every other medical procedure, it is necessary to ensure that the results of lipolytic injections are quantified on an objective and scientific basis with comparable data. Methods In the past, the size of fat tissue could not be measured properly with conventional ultrasound systems. High-resolution, real-time three-dimensional (RT-3D) ultrasound is a fairly new method for measuring the volume of tissue. Therefore, this study aimed to measure the interscapular fat bodies of New Zealand rabbits before and after lipolytic therapy with Lipostabil (R), phosphatidycholine and orciprenalin (Alupent (R)). Results The ultrasound-controlled injection of the lipolytic substances into the interscapular fat body ensured a precise injection. The RT-3D ultrasound data were compared with the magnetic resonance imaging (MRI) measurements performed at the same time. The greatest decrease in volume, up to 44%, was measured with orciprenalin (Alupent (R)). There was a significant correlation between the data from ultrasound imaging and MRI. Conclusion The data suggest that RT-3D ultrasound imaging could be a simple and fast method for proving the effects on volume size after lipolytic procedures. Of the three investigated substances, orciprenalin (Alupent (R)) showed the highest lipolytic effect in our animal model.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | FAT TISSUE; ULTRASOUND; PHOSPHATIDYLCHOLINE; TUMORS; lipolytic injection therapies; magnetic resonance imaging; real-time three-dimensional imaging |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Pathologie Medicine > Lehrstuhl für Röntgendiagnostik Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Plastische-, Hand- und Wiederherstellungschirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 28 Oct 2020 09:08 |
| Last Modified: | 28 Oct 2020 09:08 |
| URI: | https://pred.uni-regensburg.de/id/eprint/30630 |
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