Hempel, U. and Schaeffler, A. and Salzberger, B. and Ruemmele, P. and Schoelmerich, J. (2008) A 42-year-old farmer with nonspecific leucocytosis and elevated transaminases. INTERNIST, 49 (6). pp. 743-746. ISSN 0020-9554,
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We report about a 42-year-old farmer with leucocytosis, elevation of transaminases and liver cirrhosis as an underlying condition. The diagnosis of Q fever hepatitis was made through liver biopsy and serology. Under therapy with doxycycline, transaminases initially increased again; after switching to ciprofloxacin, the patient could be discharged 3 weeks after admission. Q fever is caused by Coxiella burnetii. The most frequent acute manifestation is a self-limiting flu-like illness. Chronic Q fever mostly presents as endocarditis. The diagnosis is made through histology ("doughnut" granulomas), PCR, serology (acute: anti-phase II antibodies, chronic: anti-phase I antibodies) and culture. Standard therapy is doxycycline.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Q-FEVER ENDOCARDITIS; Q-fever; Coxiella burnetii; doughnut granulomas; granulomatous hepatitis |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin I Medicine > Lehrstuhl für Pathologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 02 Nov 2020 05:53 |
| Last Modified: | 02 Nov 2020 05:53 |
| URI: | https://pred.uni-regensburg.de/id/eprint/30807 |
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