Schmid, Christof and Jurmann, Michael and Birnbaum, Dietrich and Colombo, Tiziano and Falk, Volkmar and Feltrin, Giuseppe and Garatti, Andrea and Genoni, Michele and Gerosa, Gino and Goettel, Peter and Gummert, Jan and Halfmann, Robert and Hammel, Dieter and Hennig, Ewald and Kaufmann, Friedrich and Lanfranconi, Marco and Meyns, Bart and Mohr, Friedrich and Mueller, Johannes and Nikolov, Dimitar and Rucinskas, Kestutis and Scheld, Hans-Heinrich and Schmid, Franz-Xaver and Schneider, Michael and Sirvydis, Vytautas and Tandler, Rene and Vitali, Ettore and Vlasselaers, Dirk and Weyand, Michael and Wilhelm, Markus and Hetzer, Roland (2008) Influence of inflow cannula length in axial-flow pumps on neurologic adverse event rate: Results from a multi-center analysis. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 27 (3). pp. 253-260. ISSN 1053-2498,
Full text not available from this repository. (Request a copy)Abstract
Background: The application of axial-flow pumps in patients with end-stage heart failure reveals a significantly reduced infectious complication rate as compared with rates observed with pulsatile devices. The remaining adverse event rate relates mainly to thromboembolic complications with neurologic consequences. We investigated the dependence of the neurologic adverse event rate on the length of the inflow cannula. Methods: A total of 216 consecutive patients with an axial-flow pump (INCOR; Berlin Heart GmbH, Berlin, Germany) were included in a retrospective multi-center analysis. In 138 patients, a short inflow cannula (24-mm tip length into the left ventricle), and in 78 patients a long inflow cannula (tip length 34 mm) was applied. Results: Patients with a long inflow cannula (LC) demonstrated a better survival rate than those with a short inflow cannula (SC) at the end of the observation period (LC, 63.4%; SC, 52.9%; p = 0.05). The thromboembolic adverse event rate was also significantly lower. Only 3 of the 78 patients (3.8%) with an LC had a thromboembotic adverse event (thromboembolic events per patient-year = 0.11) as compared with 32 (23.2%) of SC patients (thromboembolic events per patient-year = 0.50, P < 0.001). Conclusions: Patients with a long inflow cannula had a better survival rate and a lower incidence of cerebrovascular adverse events than patients with a short inflow cannula.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | VENTRICULAR ASSIST DEVICE; MECHANICAL CIRCULATORY SUPPORT; 1ST CLINICAL-EXPERIENCE; IMPLANTATION; INHALATION; CONDUIT; SYSTEM; INCOR; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 09 Nov 2020 05:28 |
| Last Modified: | 09 Nov 2020 05:28 |
| URI: | https://pred.uni-regensburg.de/id/eprint/31277 |
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