Diastereoselective synthesis of 3-substituted acylamino-3,4-dihydro-1,2,4-triazinones

Egorov, Ilya N. and Koenig, Burkhard and Rusinov, Vladimir L. and Chupakhin, Oleg N. (2008) Diastereoselective synthesis of 3-substituted acylamino-3,4-dihydro-1,2,4-triazinones. MENDELEEV COMMUNICATIONS, 18 (2). pp. 99-101. ISSN 0959-9436,

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Abstract

6-Phenyl-1,2,4-triazin-5(4H)-one 1 reacts with C-nucleophiles, such as indole, in the presence of N-acetylamino acids, to yield 2-acyl-3-indolyl-6-phenyl-3,4-dihydro-1,2,4-triazin-5(4H)-ones 2-6 with high diastereoselectivity.

Item Type: Article
Uncontrolled Keywords: ASYMMETRIC-SYNTHESIS;
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Depositing User: Dr. Gernot Deinzer
Date Deposited: 09 Nov 2020 07:38
Last Modified: 09 Nov 2020 07:38
URI: https://pred.uni-regensburg.de/id/eprint/31301

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