Valaikiene, J. and Schuierer, G. and Ziennus, B. and Dietrich, J. and Bogdahn, U. and Schlachetzki, F. (2008) Transcranial color-coded duplex sonography for detection of distal internal carotid artery stenosis. AMERICAN JOURNAL OF NEURORADIOLOGY, 29 (2). pp. 347-353. ISSN 0195-6108, 1936-959X
Full text not available from this repository. (Request a copy)Abstract
BACKGROUND AND PURPOSE: Gradation of high-grade intracranial internal carotid artery (ICA) stenosis poses a challenge to noninvasive neurovascular imaging, which seems critical for angioplasty in the ICA segments C1 and C5. We investigated cutoff values of intracranial ICA stenosis for transcranial color-coded sonography (TCCS) and compared this method with the "gold standard," digital subtraction angiography (DSA). MATERIALS AND METHODS: Forty patients (mean age, 58.9 +/- 13.8 years) with intracranial ICA lesions were prospectively examined by using TCCS and DSA. Two standard TCCS coronal imaging planes were used to evaluate the intracranial ICA. In addition, a control group of 128 volunteers without cerebrovascular disease (mean age, 48.8 +/- 15.9 years) was investigated to establish standard velocity values. RESULTS: DSA confirmed 96 stenoses and 8 occlusions of the intracranial ICA in the study population. in 9% and 7% of cases, stenosis confined to the C1 or C5 segment was > 50% and 70%, respectively. Receiver-operating curves demonstrated cutoff values for > 70% stenosis in C1 when the peak systolic velocity (PSV) was > 200 cm/s (specificity, 100%; sensitivity, 71 %) or the C1/submandibular ICA index was > 3 (specificity, 93%; sensitivity, 86%). CONCLUSIONS: TCCS is a reliable adjunctive method to detect and quantify significant stenosis of the intracranial ICA. The assessment of the C1/ICA index and peak systolic velocities maximizes the diagnostic accuracy of C1 stenosis to > 70% when extracranial ICA stenosis coexists. Further studies need to be performed to compare the diagnostic accuracies of MR angiography and TCCS with that of DSA.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | INTRACRANIAL VASCULAR-DISEASE; CEREBROVASCULAR-DISEASE; MUSICAL MURMURS; MR-ANGIOGRAPHY; ANGIOPLASTY; SIPHON; ATHEROSCLEROSIS; ENDARTERECTOMY; STROKE; LIMITATIONS; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Neurologie Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 09 Nov 2020 12:31 |
| Last Modified: | 09 Nov 2020 12:31 |
| URI: | https://pred.uni-regensburg.de/id/eprint/31385 |
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