Franzen, Caspar and Salzberger, Bernd (2008) Analysis of the beta-tubulin gene from Vittaforma corneae suggests benzimidazole resistance. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 52 (2). pp. 790-793. ISSN 0066-4804, 1098-6596
Full text not available from this repository. (Request a copy)Abstract
We amplified, cloned, and sequenced the beta-tubulin gene of Vittaforma corneae, a microsporidium causing human infections. The beta-tubulin gene sequence has a substitution at Glu(198) (with glutamine), which is one of six amino acids reported to be associated with benzimidazole sensitivity. Benzimidazoles were assayed for antimicrosporidial activity and showed poor parasite inhibition.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MICROSPORIDIAL KERATITIS; NOSEMA-CORNEUM; ATHYMIC MICE; IN-VITRO; IDENTIFICATION; SENSITIVITY; ALBENDAZOLE; INFECTION; DIAGNOSIS; PATIENT; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin I |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 09 Nov 2020 12:34 |
| Last Modified: | 09 Nov 2020 12:34 |
| URI: | https://pred.uni-regensburg.de/id/eprint/31389 |
Actions (login required)
 |
View Item |
