Azo pigments and a basal cell carcinoma at the thumb

Engel, Eva and Ulrich, Heidi and Vasold, Rudolf and Koenig, Burkhard and Landthaler, Michael and Suettinger, Rudolf and Baeumler, Wolfgang (2008) Azo pigments and a basal cell carcinoma at the thumb. DERMATOLOGY, 216 (1). pp. 76-80. ISSN 1018-8665, 1421-9832

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Abstract

Basal cell carcinoma is the most common malignant neoplasm of the skin, whereas the localization at the nail unit is very rare. We report the case of a 58-year-old patient with a periungual basal cell carcinoma at the thumb. The specific feature of the reported case is the frequent exposure to fishing baits that the patient had stained with an unknown colorant. The use of chromatography, mass spectrometry and infrared spectroscopy revealed the colorant as the azo pigment Solvent Red 8. Solvent Red 8 is a widespread synthetic azo pigment that is applied to stain consumer products. Compounds such as Solvent Red 8 can be cleaved to carcinogenic amines under, for example, light exposure, in particular after incorporation into the human body. As a result of the frequent skin contact to this azo pigment, this hazard compound might have induced the basal cell carcinoma in our patient. Copyright (C) 2008 S. Karger AG, Basel.

Item Type: Article
Uncontrolled Keywords: TATTOO PIGMENTS; MALIGNANT-MELANOMA; LASER; azo pigment; chromium; basal cell carcinoma
Subjects: 500 Science > 540 Chemistry & allied sciences
600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Dermatologie und Venerologie
Chemistry and Pharmacy > Institut für Organische Chemie
Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Depositing User: Dr. Gernot Deinzer
Date Deposited: 11 Nov 2020 12:39
Last Modified: 11 Nov 2020 12:39
URI: https://pred.uni-regensburg.de/id/eprint/31618

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