Nevus marginatus: a distinct type of epidermal nevus or merely a variant of nevus sebaceus?

Hafner, Christian and Landthaler, Michael and Happle, Rudolf and Vogt, Thomas (2008) Nevus marginatus: a distinct type of epidermal nevus or merely a variant of nevus sebaceus? DERMATOLOGY, 216 (3). pp. 236-238. ISSN 1018-8665,

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Abstract

Epidermal nevi (EN) represent a heterogeneous group of mosaic skin lesions frequently following the lines of Blaschko. They are divided into organoid and nonorganoid types. Herein we report on a 35-year-old man with a rather unusual type of EN. A linear lesion involving the trunk and following Blaschko's lines was conspicuously bordered by dark brown papules. The flat reddish central area histopathologically showed sebaceous hyperplasia consistent with nevus sebaceus, an organoid EN type, whereas the elevated margin showed features of a common nonorganoid keratinocytic EN. For this peculiar disorder, we propose the term 'nevus marginatus'. So far it is not clear whether nevus marginatus represents a distinct entity or merely an unusual clinical variant of nevus sebaceus. Copyright (c) 2008 S. Karger AG, Basel.

Item Type: Article
Uncontrolled Keywords: HUMAN SKIN; MUTATIONS; MOSAICISM; GENE; congenital; epidermal nevus; sebaceous gland
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Dermatologie und Venerologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 11 Nov 2020 12:39
Last Modified: 11 Nov 2020 12:39
URI: https://pred.uni-regensburg.de/id/eprint/31619

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