Hausner, Helmut and Wittmann, Markus and Hajak, Goeran and Haen, Ekkehard (2008) Sex differences in psychiatric polypharmacy. PSYCHOPHARMAKOTHERAPIE, 15 (1). 21-+. ISSN 0944-6877,
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Background: It is presumed that women are more often affected by polypharmacy than men. This assumption could be important because of hormonal and constitutional gender differences influencing pharmacodynamic and pharmacokinetic factors. The aim of this study was to test the hypothesis that multi drug use of hospitalised psychiatric patients shows sex differences. Methods: Using the AGATE census days for prescription of drugs to inpatients in 1999-2004, we examined the relationship between sex and drug use. Data were analysed by chi-square test (2-sided) using SPSS. Results: Overall 72,260 patients were evaluated at the 12 census days during the 6 years. Female patients had prescribed significantly more drugs than male patients IF: 3.7 per day; M: 2.8 per day; p<0.001). There was a similar finding in the subanalysis of patients suffering from schizophrenia (F: 3.4 per day; M: 3.0 per day; p<0.001) or depression IF: 4.6 per day; M: 4.0 per day; P<0.001). Conclusions: Hospitalised women with mental disorder are more often affected by polypharmacy than men.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | GENDER; aGATE; polypharmacy; gender |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehreinheit Pharmakologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 23 Nov 2020 10:35 |
| Last Modified: | 23 Nov 2020 10:35 |
| URI: | https://pred.uni-regensburg.de/id/eprint/31767 |
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