Berghof, L. and Bolle, I. and Schulz, A. and Grifka, J. and Quint, U. (2008) Percutaneous lumbar interbody fusion using autogenous osteoblasts in vivo. ZEITSCHRIFT FUR ORTHOPADIE UND UNFALLCHIRURGIE, 146 (1). pp. 70-74. ISSN 1864-6697, 1864-6743
Full text not available from this repository. (Request a copy)Abstract
Aim: In the present study we have investigated the potential of autogenous osteoblasts for osteoinduction in a spinal arthrodesis model. Method: After posterolateral instrumentation of 3 segments of a sheep spine the intervertebral space was filled with cancellous bone, osteoblasts OF left empty after nucleotomy and elimination of cartilage. Results: Radiological and histological analyses proved a significant osseous reaction in segments treated with cancellous bone or osteoblasts in contrast to the control segment. This outcome provides evidence of spondylodeses by spinal instrumentation in combination with osteoblasts in a sheep model. Conclusion: The results suggest a possible application of autologous osteoblasts as an osteoinductor after percutaneous nucleotomy in spinal fusion. The possible application in a human model should be examined.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SPINAL-FUSION; INSTRUMENTATION; VITRO; CELLS; interbody fusion; PLIF; ALIF; autogenous osteoblasts; cancellous bone |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Orthopädie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 24 Nov 2020 13:37 |
| Last Modified: | 24 Nov 2020 13:37 |
| URI: | https://pred.uni-regensburg.de/id/eprint/31791 |
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