Lima, Eduardo R. A. and Biscaia, Evaristo C. and Bostroem, Mathias and Tavares, Frederico W. and Prausnitz, John M. (2007) Osmotic second virial coefficients and phase diagrams for aqueous proteins from a much-improved Poisson-Boltzmann equation. JOURNAL OF PHYSICAL CHEMISTRY C, 111 (43). pp. 16055-16059. ISSN 1932-7447,
Full text not available from this repository. (Request a copy)Abstract
A much-improved Poisson -Boltzmann equation for two globular proteins using bispherical coordinates is used to establish the potential of mean force (PMF) between two globular lysozyme particles. Calculations presented here include previously ignored ion-protein none ectro static potentials. The lysozyme-lysozyme PMF is used to calculate osmotic second virial coeffiencients. The theoretical PMF curve as a function of sodium chloride concentration is successfully compared with that from experiment. Our theoretical PMF shows how the second virial coefficient and the phase diagram depends on salt concentration, pH and, most notably, on the choice of salt in the aquous solution.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SPHERICAL COLLOIDAL PARTICLES; HOFMEISTER-SERIES; RELATIVE EFFECTIVENESS; SALT IDENTITY; LYSOZYME; FORCES; PH; CRYSTALLIZATION; SOLUBILITY; SURFACE; |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Physikalische und Theoretische Chemie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 30 Nov 2020 14:06 |
| Last Modified: | 30 Nov 2020 14:06 |
| URI: | https://pred.uni-regensburg.de/id/eprint/31989 |
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