Schumacher, Axel and Friedrich, Patricia and Diehl-Schmid, Janine and Ibach, Bernd and Eisele, Tamara and Laws, Simon M. and Foerstl, Hans and Kurz, Alexander and Riemenschneider, Matthias (2007) No association of chromatin-modifying protein 2B with sporadic frontotemporal dementia. NEUROBIOLOGY OF AGING, 28 (11). pp. 1789-1790. ISSN 0197-4580,
Full text not available from this repository. (Request a copy)Abstract
Mutations of the chromatin modifying protein 213 gene (CHMP2B) were identified, in a Danish pedigree, to cause familial frontotemporal dementia (FTD). To explore the possible genetic contribution of common CHMP2B variants in sporadic FFD, we analyzed 14 single nucleotide polymorphisms covering the entire genomic region of CHMP2B. After adjustment for multiple testing single marker and haplotype analysis revealed no significant association with sporadic FTD. Thus, we conclude that CHMP2B can be excluded as a susceptibility gene conferring risk to sporadic forms of FTD. (c) 2006 Elsevier Inc. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PARKINSONS-DISEASE; LOBAR DEGENERATION; MUTATIONS; CHMP2B; CHMP2B; POU1F1; frontotemporal dementia; genetic analysis; association study |
| Subjects: | 100 Philosophy & psychology > 150 Psychology |
| Divisions: | Human Sciences > Institut für Psychologie > Lehrstuhl für Klinische Psychologie und Psychotherapie - Lehrstuhl für Psychologie VIII - Prof. Dr. Andreas Mühlberger |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 30 Nov 2020 15:14 |
| Last Modified: | 30 Nov 2020 15:14 |
| URI: | https://pred.uni-regensburg.de/id/eprint/32027 |
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