Budweiser, Stephan and Joerres, Rudolf A. and Criee, Carl-Peter and Langer, Veronika and Heinemann, Frank and Hitzl, Andre P. and Schmidbauer, Kathrin and Windisch, Wolfram and Pfeifer, Michael (2007) Prognostic value of mouth occlusion pressure in patients with chronic ventilatory failure. RESPIRATORY MEDICINE, 101 (11). pp. 2343-2351. ISSN 0954-6111,
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Background: Mouth occlusion pressure measurement is widely used for assessment of respiratory muscle function, particularly in patients with respiratory failure. However, its predictive value for long-term survival remains largely unexplored. Methods: In 464 patients with chronic hypercapnic respiratory failure (CHRF) due to various underlying disorders and receiving non-invasive ventilation (NIV), maximal inspiratory mouth pressure (PImax), mouth occlusion pressure at 100ms during quiet breathing (P-0.1) and the ratio P-0.1/PImax were assessed prior to and after treatment including NIV. Baseline data and changes at follow-up were used to evaluate their predictive value for tong-term survival. Results: Overall, median (quartiles) P0.1 was 177.0 (109.2;287.0) %pred, PImax 35.0 (24.0;47.0) %pred, and P-0.1/P-max 564.0 (275.7;1082.3) %pred. In multivariate analyses, P0.1 was related to airflow obstruction, lung hyperinflation, haemoglobin (Hb) and leukocytes, and PImax to airflow obstruction and hyperinflation (p<0.05 each). All-cause
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | OBSTRUCTIVE PULMONARY-DISEASE; RESTRICTIVE THORACIC DISEASE; RANDOMIZED CONTROLLED-TRIAL; MECHANICAL VENTILATION; RESPIRATORY-FAILURE; NONINVASIVE VENTILATION; MUSCLE STRENGTH; OXYGEN-THERAPY; COPD; SURVIVAL; chronic respiratory failure; inspiratory muscle strength; mortality; prognostic factors; respiratory muscles |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin II |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 01 Dec 2020 11:57 |
| Last Modified: | 01 Dec 2020 11:57 |
| URI: | https://pred.uni-regensburg.de/id/eprint/32047 |
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