Zaak, D. and Karl, A. and Stepp, H. and Tritschler, S. and Tilki, D. and Burger, M. and Wieland, W. F. and Knuechel, R. and Stief, C. (2007) Fluorescence cystoscopy at bladder cancer - Aktueller stellenwert. UROLOGE, 46 (11). 1519-+. ISSN 1433-0563,
Full text not available from this repository. (Request a copy)Abstract
Bladder cancer is a frequent disease and represents the second most common genitourinary neoplasm. Although many aspects of the management of not-muscle-infiltrating bladder cancer are now well established, significant challenges remain, which influence patient outcome. Early detection and treatment of recurrent disease is required to optimize bladder preservation, reduce patient morbidity and increase quality of life and survival. Fluorescence cystoscopy, often referred to as "photodynamic diagnosis" (PDD) with intravesical application of photosensitizing agents has been developed in order to enhance the early detection of bladder cancer. Since March 2005 the hexyl-ALA ester (Hexvix (R)) has been approved for the diagnosis of bladder cancer in 27 EU/EEA countries through the European Mutual Recognition Procedure. There is growing evidence that PDD enhances the detection of bladder cancer, particularly of high-grade flat lesions. Furthermore, transurethral resection of bladder tumor under fluorescence guidance has been shown to reduce the risk of recurrent tumors. Nevertheless, a resulting relatively decreased number of recurrences have still to be verified in prospective randomized trials.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | TRANSITIONAL-CELL CARCINOMA; WHITE-LIGHT CYSTOSCOPY; FLAT UROTHELIAL HYPERPLASIAS; INDUCED PROTOPORPHYRIN-IX; 5-AMINOLEVULINIC ACID; TRANSURETHRAL RESECTION; PHASE-III; IN-SITU; PHOTODYNAMIC DIAGNOSIS; ENDOSCOPY; fluorescence cystoscopy; bladder cancer; photodynamic diagnosis; hexyl-ALA ester |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Urologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 01 Dec 2020 12:21 |
| Last Modified: | 01 Dec 2020 12:21 |
| URI: | https://pred.uni-regensburg.de/id/eprint/32053 |
Actions (login required)
 |
View Item |
