Stein, Franziska and Kobor, Ines and Bogdahn, Ulrich and Schulte-Mattler, Wilhelm J. (2016) Toward the validation of a new method (MUNIX) for motor unit number assessment. JOURNAL OF ELECTROMYOGRAPHY AND KINESIOLOGY, 27. pp. 73-77. ISSN 1050-6411, 1873-5711
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Introduction: This prospectively designed study analyzed the correlation of a new, non-invasive neurophysiological method (Motor Unit Number Index -MUNIX) with two established Motor Unit Number Estimation (MUNE) methods. Methods: MUNIX and incremental stimulation MUNE (IS-MUNE) were done in the abductor digiti minimi muscle (ADM), while MUNIX and spike-triggered averaging MUNE (STA-MUNE) were tested in the trapezius muscle. Twenty healthy subjects and 17 patients with amyotrophic lateral sclerosis (ALS) were examined. Results: MUNIX and MUNE values correlated significantly (ADM: n = 108; Spearman-Rho; r = 0.88; p < 0.01; trapezius muscle: n = 49; Spearman-Rho; r = 0.46; p < 0.01). Discussion: MUNIX indeed reflects the number of motor units in a muscle, and may sensibly be recorded from the trapezius muscle. With MUNIX being both much more patient friendly and much more rapid to assess than MUNE, the results support the use of MUNIX when motor unit number assessment is desired. (C) 2016 Elsevier Ltd. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | AMYOTROPHIC-LATERAL-SCLEROSIS; INDEX MUNIX; NEURON DISEASE; HUMAN MUSCLES; ALS PATIENTS; REPRODUCIBILITY; Amyotrophic lateral sclerosis; Motor unit number index; Motor unit number estimation; Spike-triggered averaging motor unit number estimation; Incremental stimulation motor unit number estimation |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Neurologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 25 Mar 2019 14:35 |
| Last Modified: | 25 Mar 2019 14:35 |
| URI: | https://pred.uni-regensburg.de/id/eprint/3212 |
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