Heitzmann, Dirk and Warth, Richard (2007) No potassium, no acid: K+ channels and gastric acid secretion. PHYSIOLOGY, 22 (5). pp. 335-341. ISSN 1548-9213, 1548-9221
Full text not available from this repository. (Request a copy)Abstract
The gastric H+-K+-ATPase pumps H+ into the lumen and takes up K+ in parallel. In the acid-producing parietal cells, luminal KCNE2/KCNQ1 K+ channels play a pivotal role in replenishing K+ in the luminal fluid. Inactivation of KCNE2/KCNQ1 channels abrogates gastric acid secretion and dramatically modifies the architecture of gastric mucosa.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | UNION-OF-PHARMACOLOGY; CALCIUM-SENSING RECEPTOR; RABBIT PARIETAL-CELLS; OXYNTIC CELLS; MOLECULAR RELATIONSHIPS; TARGETED DISRUPTION; NA+/H+ EXCHANGER; APICAL MEMBRANE; CL CONDUCTANCES; BASOLATERAL LOCALIZATION; |
| Subjects: | 500 Science > 570 Life sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Richard Warth |
| Depositing User: | Petra Gürster |
| Date Deposited: | 04 Dec 2020 08:12 |
| Last Modified: | 04 Dec 2020 08:12 |
| URI: | https://pred.uni-regensburg.de/id/eprint/32184 |
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