Wertz, H. and Lohr, F. and Dobler, B. and Mai, S. and Welzel, G. and Boda-Heggemann, J. and Wenz, F. (2007) Dosimetric consequences of a translational isocenter correction based on image guidance for intensity modulated radiotherapy (IMRT) of the prostate. PHYSICS IN MEDICINE AND BIOLOGY, 52 (18). pp. 5655-5665. ISSN 0031-9155,
Full text not available from this repository. (Request a copy)Abstract
Interfractional prostate motion during radiotherapy can have deleterious clinical consequences. It has become clinical practice to re-position the patient according to ultrasound or other imaging techniques. We investigated the dosimetric consequences of the linear translational position correction (isocenter correction) when a conformal IMRT technique with nine fields was used. Treatment plans of seven patients with empty and distended rectums were analyzed. The reference plans were calculated on the CT with an empty rectum. The treatment plans were transferred to a second CT with a distended rectum for an uncorrected setup of the patient referenced to bony anatomy and a corrected setup after translational position correction of the isocenter. The dosimetric consequences (with and without correction) were analyzed. For single treatment fractions, organ motion decreased the volume of the prostate encompassed by the 95% isodose (V95%) by up to -24%-p (percentage points). The mean rectum dose increased by up to 41%-p. Linear translational correction increased V95% of the prostate by up to 17%-p while the mean rectum dose was reduced by up to -23%-p compared to the uncorrected setup. Linear translational correction can improve radiation treatment accuracy for prostate cancer if geometrical changes are within certain limits.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | EXTERNAL-BEAM RADIOTHERAPY; ADAPTIVE RADIATION-THERAPY; CONFORMAL RADIOTHERAPY; ORGAN MOTION; POSITION VARIABILITY; DOSE DISTRIBUTIONS; SEMINAL-VESICLES; SETUP ERRORS; CANCER; LOCALIZATION; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Strahlentherapie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 01 Dec 2020 07:07 |
| Last Modified: | 01 Dec 2020 07:07 |
| URI: | https://pred.uni-regensburg.de/id/eprint/32201 |
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