Bacterial colonization is of major relevance for high-grade capsular contracture after augmentation mammaplasty

Schreml, Stephan and Heine, Norbert and Eisenmann-Klein, Marita and Prantl, Lukas (2007) Bacterial colonization is of major relevance for high-grade capsular contracture after augmentation mammaplasty. ANNALS OF PLASTIC SURGERY, 59 (2). pp. 126-130. ISSN 0148-7043,

Full text not available from this repository.

Abstract

Many studies indicate that subclinical bacteria colonization plays a pivotal role in capsular contracture. Nevertheless, it has not been clarified whether bacteria] stimuli are only associated with high-grade (Baker III/IV) or low-grade (Baker I/II) capsular contractures. The study included 45 female patients suffering from unilateral capsular fibrosis following augmentation mammaplasty with silicone implants (smooth: n = 28; textured: n = 17). In total, there were 16 (35.6%) bacterially contaminated swabs. No significant difference could be, detected between colonization rates of smooth (52.9%) and textured (25.0%) implants (z = 1.575, P = 0.115). Interestingly, no colonization was detected for Baker I/II contractures, but the colonization rate for Baker III/IV contractures amounted to 66.7%, showing a highly significant difference between the 2 groups (z = 4.351, P < 0.001). Our study shows significant differences in bacterial contamination rates between high-grade and low-grade capsular contractures. One might speculate that bacterial stimuli accelerate the process of inflammation and fibrosis in patients who tend to develop capsular fibrosis.

Item Type: Article
Uncontrolled Keywords: TOLL-LIKE RECEPTORS; BREAST IMPLANTS; IN-VITRO; SUBCLINICAL INFECTION; SILICONE IMPLANTS; ADHESION; SURFACE; ANTIBIOTICS; OUTCOMES; bacterial colonization; breast implants; capsular contracture; augmentation mammaplasty
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Plastische-, Hand- und Wiederherstellungschirurgie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 01 Dec 2020 14:38
Last Modified: 01 Dec 2020 14:38
URI: https://pred.uni-regensburg.de/id/eprint/32411

Actions (login required)

View Item View Item