Reduced TH-1 cytokine release in an adult patient with chronic relapsing Mycobacterium malmoense infection

Sahrbacher, U. and Naumann, L. and Reischl, U. and Schoelmerich, J. and Glueck, T. (2007) Reduced TH-1 cytokine release in an adult patient with chronic relapsing Mycobacterium malmoense infection. INFECTION, 35 (4). pp. 282-286. ISSN 0300-8126,

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Abstract

An unusual course of infection with Mycobacterium malmoense is described in a patient receiving chronic but mild immunosuppressive therapy for rheumatoid arthritis. Symptoms mimicking Crohn's disease deteriorated under intensified immunosuppression and surgery. Judging from the patient's course under treatment specific for M. malmoense, the gastrointestinal symptoms were rather manifestations of a chronic relapsing mycobacterial infection. Detailed immunological investigation of the patient revealed a severely impaired TH-1 cytokine response as the immunological background for this uncommon course.

Item Type: Article
Uncontrolled Keywords: INTERFERON-GAMMA; T-CELL; SUSCEPTIBILITY; IDENTIFICATION; TUBERCULOSIS;
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Innere Medizin I
Depositing User: Dr. Gernot Deinzer
Date Deposited: 01 Dec 2020 13:32
Last Modified: 01 Dec 2020 13:32
URI: https://pred.uni-regensburg.de/id/eprint/32449

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