Assessing quality of life in patients with colorectal cancer: An update of the EORTC quality of life questionnaire

Gujral, S. and Conroy, T. and Fleissner, C. and Sezer, O. and King, P. M. and Avery, K. N. L. and Sylvester, P. and Koller, M. and Sprangers, M. A. G. and Blazeby, J. M. (2007) Assessing quality of life in patients with colorectal cancer: An update of the EORTC quality of life questionnaire. EUROPEAN JOURNAL OF CANCER, 43 (10). pp. 1564-1573. ISSN 0959-8049,

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Abstract

The European Organisation for Research and Treatment of Cancer (EORTC) has a portfolio of questionnaire modules to supplement the QLQ-C30 to assess patient reported outcomes in cancer clinical trials. This study updated the module for colorectal cancer. A review of the literature identified 20 articles that used the EORTC colorectal module. Eight papers did not report data from scales addressing sexual function and 8 added additional scales to assess ano-rectal function. Interviews with patients (n = 79) and professionals (n = 11) informed item selection, reduction and modification. A new 29 item module was devised and further patient interviews (n = 120) examined its format and content validity. Patients found the new module acceptable with relevant content. The new module, the EORTC QLQ-CR29, is hypothesised as containing 6 scales and 11 single items. An international study examining its clinical and psychometric validity will be performed. (C) 2007 Elsevier Ltd. All rights reserved.

Item Type: Article
Uncontrolled Keywords: RANDOMIZED CLINICAL-TRIAL; RECTAL-CANCER; EUROPEAN-ORGANIZATION; PREOPERATIVE RADIOTHERAPY; FUNCTIONAL ASSESSMENT; MESORECTAL EXCISION; FACT-C; SURGERY; RESECTION; INSTRUMENT; colorectal cancer; quality of life; questionnaire; EORTC QLQ-CR38
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Klinische Studien
Depositing User: Dr. Gernot Deinzer
Date Deposited: 02 Dec 2020 11:44
Last Modified: 02 Dec 2020 11:44
URI: https://pred.uni-regensburg.de/id/eprint/32530

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