Knott, Juergen M. and Roemer, Piero and Sumper, Manfred (2007) Putative spermine synthases from Thalassiosira pseudonana and Arabidopsis thaliana synthesize thermospermine rather than spermine. FEBS LETTERS, 581 (16). pp. 3081-3086. ISSN 0014-5793,
Full text not available from this repository. (Request a copy)Abstract
Polyamines are involved in many fundamental cellular processes. Common polyamines are putrescine, spermidine and spermine. Spermine is synthesized by transfer of an ammopropyl residue derived from decarboxylated S-adenosylmethionine to spermidine. Thermospermine is an isomer of spermine and assumed to be synthesized by an analogous mechanism. However, none of the recently described spermine synthases was investigated for their possible activity as thermospermine synthases. In this work, putative spermine synthases from the diatom Thalassiosira pseudonana and from Arabidopsis thaliana could be identified as thermospermine synthases. These findings may explain the previous result that two putative spermine synthase genes in Arabidopsis produce completely different phenotypes in knock-out experiments. Likely, part of putative spermine synthases identifiable by sequence comparisons represents in fact thermospermine synthases. (c) 2007 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MOLECULAR-CLONING; POLYAMINES; SILICA; DIATOMS; GENE; GROWTH; thermospermine; spermine; diatom; polyamine synthesis; Arabidopsis thaliana |
| Subjects: | 500 Science > 570 Life sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Alumni or Retired > Prof. Dr. Manfred Sumper |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 07 Dec 2020 13:11 |
| Last Modified: | 07 Dec 2020 13:11 |
| URI: | https://pred.uni-regensburg.de/id/eprint/32595 |
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