Solid-phase synthesis of metal-complex containing peptides

Dirscherl, Georg and Knape, Robert and Hanson, Paul and Koenig, Burkhard (2007) Solid-phase synthesis of metal-complex containing peptides. TETRAHEDRON, 63 (23). pp. 4918-4928. ISSN 0040-4020,

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Abstract

We report the synthesis of Fmoc protected single amino acid chelates (SAAC) and their metal complexes. The modified amino acids are suitable for solid-phase peptide synthesis. The use of 4-hydroxymethylbenzoic acid AM (HMBA-AM) resin allows the nucleophilic cleavage of the peptide-metal complexes from the resin without decomplexation. (c) 2007 Elsevier Ltd. All rights reserved.

Item Type: Article
Uncontrolled Keywords: AMINO-ACID; IN-VITRO; STRATEGY; TC-99M; 1-HYDROXY-7-AZABENZOTRIAZOLE; RADIOPHARMACEUTICALS; DERIVATIVES; TECHNETIUM; LIGAND; RE; solid-phase peptide synthesis; metal complex; single amino acid chelate
Subjects: 500 Science > 540 Chemistry & allied sciences
Divisions: Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Depositing User: Dr. Gernot Deinzer
Date Deposited: 04 Dec 2020 06:54
Last Modified: 04 Dec 2020 06:54
URI: https://pred.uni-regensburg.de/id/eprint/32622

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