Stolz, Erwin and Valdueza, Jose Manuel and Grebe, Mathias and Schlachetzki, Felix and Schmitt, Eberhard and Madlener, Katharina and Rahimi, Anousha and Kempkes-Matthes, Bettina and Blaes, Franz and Gerriets, Tibo and Kaps, Manfred (2007) Anemia as a risk factor for cerebral venous thrombosis? An old hypothesis revisited. JOURNAL OF NEUROLOGY, 254 (6). pp. 729-734. ISSN 0340-5354,
Full text not available from this repository. (Request a copy)Abstract
Several case reports have linked iron deficiency anemia with the occurrence of cerebral venous thrombosis (CVT) or stroke, yet, it is unclear whether this is a chance association. In a case-control design data of whole blood count and screening for thrombophilic coagulation abnormalities of 121 prospectively identified patients with CVT and 120 healthy controls were compared. Anemia was defined as a hemoglobin (Hb) concentration of < 120 g/l in females, and < 130 g/l in males, severe anemia as a Hb < 90 g/l. Adjusted odds ratios (OR) were calculated based on a logistic regression model treating variables with a level of significance of p <= 0.2 on univariate analysis as potential confounders. Thrombophilia (OR 1.22, 95% CI 1.07-1.76, p < 0.01), severe anemia (OR 1.10, 95% CI 1.01-2.22, p < 0.05), and hypercholesterinemia (OR 1.21, 95% CI 1.04-2.57, p < 0.05) were the only independent variables associated with CVT on multivariate analysis. Severe anemia is significantly and independently associated with CVT.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | IRON-DEFICIENCY ANEMIA; PLATELET-AGGREGATION; IN-VITRO; THROMBOCYTOSIS; COAGULATION; CHILDREN; INFANTS; STROKE; SINUS; sinus thrombosis; thrombophilia; anemia; stroke |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Neurologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 04 Dec 2020 09:32 |
| Last Modified: | 04 Dec 2020 09:32 |
| URI: | https://pred.uni-regensburg.de/id/eprint/32689 |
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